منابع مشابه
Diagnostic reliability of bipolar II disorder.
BACKGROUND Although the diagnostic reliability of major depression and mania has been well established, that of hypomania and bipolar II (BPII) disorder has not. This remains an important issue for clinicians, especially for those undertaking genetic studies of BP disorder since bipolar I (BPI) and BPII disorders often cluster in the same families. We have assessed our diagnostic reliability of...
متن کاملHistorical Underpinnings of Bipolar Disorder Diagnostic Criteria
Mood is the changing expression of emotion and can be described as a spectrum. The outermost ends of this spectrum highlight two states, the lowest low, melancholia, and the highest high, mania. These mood extremes have been documented repeatedly in human history, being first systematically described by Hippocrates. Nineteenth century contemporaries Falret and Baillarger described two forms of ...
متن کاملDiagnostic specificity of neurophysiological endophenotypes in schizophrenia and bipolar disorder.
BACKGROUND The utility of an endophenotype depends on its ability to reduce complex disorders into stable, genetically linked phenotypes. P50 and P300 event-related potential (ERP) measures are endophenotype candidates for schizophrenia; however, their abnormalities are broadly observed across neuropsychiatric disorders. This study examined the diagnostic efficiency of P50 and P300 in schizophr...
متن کاملBipolar Disorder 3 Treatment of bipolar disorder
We review recent developments in the acute and long-term treatment of bipolar disorder and identify promising future routes to therapeutic innovation. Overall, advances in drug treatment remain quite modest. Antipsychotic drugs are effective in the acute treatment of mania; their efficacy in the treatment of depression is variable with the clearest evidence for quetiapine. Despite their widespr...
متن کاملTowards a blood-based diagnostic panel for bipolar disorder
BACKGROUND Bipolar disorder (BD) is a costly, devastating and life shortening mental disorder that is often misdiagnosed, especially on initial presentation. Misdiagnosis frequently results in ineffective treatment. We investigated the utility of a biomarker panel as a diagnostic test for BD. METHODS AND FINDINGS We performed a meta-analysis of eight case-control studies to define a diagnosti...
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ژورنال
عنوان ژورنال: BJPsych Advances
سال: 2017
ISSN: 2056-4678,2056-4686
DOI: 10.1192/apt.bp.115.015305